miR-489-3p/SIX1 Axis Regulates Melanoma Proliferation and Glycolytic Potential
نویسندگان
چکیده
منابع مشابه
The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
Objective(s): To explore the correlation between expression patterns and functions of miR-383 and LDHA in hepatocellular cancer (HCC). Materials and Methods: We detected the expression of miR-383 and LDHA in 30 HCC tissues and their matched adjacent normal tissues using qRT-PCR. Then we performed MTT assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...
متن کاملthe mir-383-ldha axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...
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BACKGROUND The Yin Yang 1 (YY1) transcription factor has been identified to target a plethora of potential target genes, which are important for cell proliferation and differentiation. Although the role that YY1 plays in different human types of cancer has been reported, its biological and mechanistic significance in melanoma has not been well defined. METHODS Quantitative RT-PCR analysis was...
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ژورنال
عنوان ژورنال: Molecular Therapy - Oncolytics
سال: 2020
ISSN: 2372-7705
DOI: 10.1016/j.omto.2019.11.001